Top stories
PANORAMIC trial finds molnupiravir may not be a cost-effective treatment for COVID-19 in at-risk adults
28 January 2024
A new evaluation from the University of Oxford’s ongoing PANORAMIC trial suggests that an antiviral treatment, called molnupiravir, used to treat COVID-19 may not be cost-effective at its current price of £513 per course, compared to usual NHS care and support, in the first six months after infection. However, it may be beneficial for patients over the age of 75.
New antiviral, Paxlovid, added to PANORAMIC study
12 April 2022
General New medications Research
From today, the antiviral treatment Paxlovid has been included in the national PANORAMIC study, the UK’s fastest ever recruiting clinical trial of its kind, run by the Nuffield Department of Primary Care Health Sciences and supported by the National Institute for Health and Care research (NIHR).
News and updates from the PANORAMIC team
Celebrating innovation: the PRINCIPLE-PANORAMIC Celebratory Symposium
17 April 2024
Researchers, clinicians, supporters and PPI contributors gathered on Monday to celebrate the innovative PRINCIPLE and PANORAMIC clinical trials that evaluated potential treatments for COVID-19 during the pandemic and broke recruitment records for community-based trials in doing so. Both trials were run by the Clinical Trails Unit (CTU) in the Nuffield Department of Primary Care Health Sciences (NDPCHS).
New study suggests antiviral treatment course is not long enough to treat COVID-19 in at risk patients
26 February 2024
New research published in Nature Communications suggests that the currently recommended five-day course of molnupiravir, an antiviral treatment, may not be long enough to treat COVID-19.
Testing Positive for COVID-19?
18 April 2023
Reflecting on PANORAMIC and PRINCIPLE, three years into the COVID-19 Pandemic
30 March 2023
Earlier this month—Saturday 11 March 2023—we marked the third anniversary of the World Health Organization (WHO) declaring the COVID-19 pandemic. This anniversary is an opportunity to reflect on the lessons learned from the pandemic and renew efforts to strengthen health systems and ensure equitable access to vaccines and treatments.
Time of India: Places of worship have huge impact on scientific studies
9 February 2023
Mahendra Patel, a professor of pharmacy working at the University of Oxford: "The government of the UK made the PRINCIPLE trial an urgent national public health priority in the search for early treatment for COVID-19 in the community to help stop people being hospitalised and to recover more quickly. Different ethnic groups have different beliefs and attitudes including those from Black and Asian ethnic minority backgrounds, How to encourage people to come forward and take part in trials? We want to ensure that recruitment was representative of our national diaspora and that the treatment was effective in all populations irrespective of their backgrounds."
Professor Chris Butler addresses the UN on PANORAMIC - BAPS UK & Europe collaboration
24 January 2023
Recently, Professor Chris Butler addressed the United Nations regarding the PANORAMIC Trial and the assistance of BAPS UK & Europe.
PANORAMIC trial finds molnupiravir does not reduce COVID-19 hospitalisation/deaths in vaccinated people at high risk
22 December 2022
Researchers from the University of Oxford have today released findings from a clinical trial investigating the effectiveness of the antiviral treatment molnupiravir against COVID-19 – the first treatment tested in the ongoing PANORAMIC trial.
British Muslim organisations support PANORAMIC ahead of Ramadan
31 March 2022
The Muslim Council of Britain (MCB) and the British Islamic Medical Association (BIMA) joined forces in March to help promote the PANORAMIC trial as part of a series of outreach activities ahead of the Muslim holy month of Ramadan, enabling greater outreach to diverse communities across Britain.
PANORAMIC hits the 20,000 participant milestone
31 March 2022
The world’s largest study of community-based treatments for acute COVID-19 has reached a world-first, historic milestone: over twenty thousand participants from across the UK have now taken part in the PANORAMIC trial.
Largest Hindu temple in Europe helps to spread awareness of the PANORAMIC study
11 March 2022
Europe’s BAPS Swaminarayan Sanstha, the largest Hindu temple outside of India, is supporting their community during the coronavirus pandemic by spreading awareness of the PANORAMIC trial of COVID-19 treatments.
Covid 19: Anti-viral drug study open to patients in NI
8 March 2022
New Story from the BBC: People in Northern Ireland are being urged to take part in a study which will help decide how antiviral drugs will be used to treat Covid-19.
University of Bolton student champions praised for support in University of Oxford Covid-19 treatment trials
24 February 2022
General New medications Recruitment
Student Champions from the University of Bolton who have helped to recruit volunteers through community outreach work for the world’s largest trials to treat Covid-19 have been congratulated for their hard work.
Over ten thousand participants enrol in world’s largest COVID-19 antiviral study
21 February 2022
Over ten thousand participants from right across the UK have now taken part in the NIHR-funded and supported PANORAMIC trial - which is by far the world’s largest study into new antiviral treatments against COVID-19 in community, ambulatory care.
BBC: Patients wanted for Oxford and Southampton Unis' take-at-home pill trial
14 February 2022
Researchers studying the use of an antiviral drug people can take at home to treat Covid want thousands more volunteers to join their trial. Scientists at Oxford and Southampton Universities are looking at how molnupiravir can reduce symptoms in people at risk of serious illness. They have signed up 8,000 recently diagnosed with the virus but want thousands more to join the trial.
BBC Inside Health (Radio 4): PANORAMIC and anti-virals featured
19 January 2022
BBC Inside Health speak to Nerys from North Wales who has started antiviral treatment for her COVID-19 infection. They also explore the new drugs with virologist Dr Elisabetta Groppelli and Professor Chris Butler who is running the clinical trial designed to pinpoint who is likely to benefit from antivirals the most. (Skip to 15min in for anti-virals).
The Guardian: How antivirals provide hope to vulnerable COVID-19 patients
18 January 2022
The recent decision by regulators to approve the antiviral agent Paxlovid for use in the UK adds a formidable new weapon to the arsenal of treatments for COVID-19.
New Scientist: UK has begun using drugs for covid-19 cases before they become severe
18 January 2022
Treatments like sotrovimab, molnupiravir and Paxlovid could lead to a new strategy in 2022: tackling COVID-19 soon after infection to prevent severe symptoms from developing
BBC: Hundreds in Wales take antiviral tablets
13 January 2022
A news story from the BBC features people taking part in PANORAMIC from Wales
Recruitment begins for national community COVID-19 antiviral trial
8 December 2021
Researchers from the University of Oxford have today started recruiting participants for a first-of-its-kind clinical trial to test novel antiviral COVID-19 treatments for use early on in the illness by people in the community with COVID-19 and those who are at higher risk of complications – partnering with the National Institute for Health Research (NIHR) and working with colleagues in several UK universities, and the NHS UK-wide.